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Infused Horadric Resin is the Magic crafting material behind the Talisman recipes of the Horadric Cube, the crafting station that Lord of Hatred brought to Diablo 4 in April 2026. You get it by salvaging Talisman Charms and Seals, and the Cube spends it to reroll Set Charms, craft Unique Charms and, from Season 15, fully reroll the base affixes of Charms and Seals.
| Item type | Magic crafting material |
|---|---|
| Used for | Crafting and rerolling Talisman Charms and Seals in the Horadric Cube |
| Source | Salvaging Talisman Charms and Seals |
| Reroll Set Charm | 1 Set Charm + 25 Raw Primordial Dust + 50 Infused Horadric Resin |
| Craft Unique Charm | 1 Ancestral Unique + 3 Unique Charms + 1 Enhanced and 50 Raw Primordial Dust + 100 Infused Horadric Resin |
| Horadric Reroll (Season 15) | Legendary or better Talisman item + 1 Pure and 100 Raw Primordial Dust + 100 Infused Horadric Resin; set bonuses and Unique powers stay |
| Affix Value Reroll (Season 15) | Infused Horadric Resin is an optional ingredient |
| Talisman | A Seal unlocks up to 6 Charm slots; Set Charms add set bonuses |
| Expansion | Horadric Cube and Talisman came with Lord of Hatred (April 2026); the Cube is found in its campaign and stays in Temis |
A Seal opens up to six Charm slots on the Talisman, and stronger Seals carry more affixes and more slots. Non-Unique Charms with the same affix stack their bonuses, while Set Charms add set bonuses that work together with your gear. Sets are either class-specific or open to every class.
From salvaging Talisman Charms and Seals, so every spare Charm you break down feeds the next reroll.
No. It randomizes base affixes only; Charm set bonuses and Unique or Mythic Charm powers stay as they are.
More answers: FAQ
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